Document Type : Original Article
Authors
1
Botany and Microbiology Department, Faculty of Science, Girls Branch, Al-Azhar University, Cairo, Egypt.
2
Botany Department, Faculty of Science, Mansoura University, Mansoura 35516, Egypt
3
Botany and Microbiology Department, Faculty of Science, Girls Branch, Al-Azhar University, Nasr City, Cairo 11884 Egypt.
Abstract
The increasing global popularity of wild plants is linked to their potential as sources of antioxidants and phytochemical components that could be used in medicine as antibacterial agents against antibiotic-resistant bacteria. This study aims to determine and compare the phytochemical secondary metabolites, essential oils, fatty constituents, free radical scavenging activity, and antibacterial potential of water, methanol, and petroleum ether extracts from the aerial parts of Leptadenia pyrotechnica (Forssk.) Decne. growing in Egypt. The results indicated that the extracts showed variable content of total phenolics, flavonoids, tannins, alkaloids, and saponins. The water extract recorded the highest secondary metabolite content and radical scavenging effect, as measured by the DPPH assay (IC50 = 0.16 mg extract/ml). GC-MS analysis revealed fifty-six volatile constituents, including thirteen non-oxygenated hydrocarbons, fourteen oxygenated hydrocarbons, eight terpenes, seventeen fatty acids and lipids, and four steroidal components. Regarding antibacterial properties, the studied extracts demonstrated antibacterial activity against Staphylococcus aureus, Listeria monocytogenes, Bacillus cereus, and Staphylococcus epidermidis. The extracts of L. pyrotechnica could be utilized as antioxidant resources, drugs, and antibacterial botanicals to combat antibiotic-resistant bacterial strains.
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